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A primary bile acid; an FXR agonist that binds to FXRs in a TR-FRET assay (EC50 = 13 µM) and induces FXR transactivation in a reporter assay; induces transcription of GCL in primary hepatocytes and HepG2 cells from 25-100 µM
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Estradiol benzoate is an HBx protein inhibitor that inhibits androgen and hepatitis B virus (HBV) transcription and replication. It demonstrates antifertility effects and anti-Toxoplasma gondii activity.
Improves memory behavior in ovariectomy (Ovx) female mice
Appearance: solid, white to off-white
For research use only
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Estradiol benzoate is a HBx protein inhibitor that inhibits androgen and hepatitis B virus (HBV) transcription and replication. It also shows antifertility effects, anti-Toxoplasma gondii activity, and can improve memory behavior in Ovariectomy (Ovx) female mice.
Inhibits HBx protein
Inhibits androgen transcription
Inhibits hepatitis B virus (HBV) transcription and replication
Exhibits antifertility effects
Shows anti-Toxoplasma gondii activity
May improve memory behavior in Ovariectomy (Ovx) female mice
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Estradiol benzoate-d3 is the deuterium labeled Estradiol benzoate. It is a proagent of estradiol that acts as a steroid sex hormone. This compound exhibits mild anabolic and metabolic properties, and increases blood coagulability. It is for research use only.
This compound can be used as a tracer.
This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
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Estradiol benzoate (β-Estradiol 3-benzoate) is an HBx protein inhibitor that inhibits androgen and hepatitis B virus (HBV) transcription and replication. It also shows antifertility effects, anti-Toxoplasma gondii activity, and can improve memory behavior in Ovariectomy (Ovx) female mice.
Inhibits HBx protein.
Suppresses androgen and hepatitis B virus (HBV) transcription and replication.
Exhibits antifertility effects.
Shows anti-Toxoplasma gondii activity.
Improves memory behavior in ovariectomy (Ovx) female mice.
Reverses lowered uterine weight in Ovx mice.
Increases number and density of synaptic vesicles.
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Estradiol benzoate (50-50-0) is a small-molecule agonist targeting estrogen receptors exhibiting high binding affinity for estrogen receptor alpha (ER ) It is designed to activate ER thereby modulating estrogen-mediated signaling pathways and hormonal regulation processes Estradiol benzoate exerts its biological activity primarily through ER agonism In in vitro assays involving human murine and chicken ER proteins estradiol benzoate demonstrates agonistic activity with an IC50 value ranging between 22 28 nM Based on these pharmacological properties estradiol benzoate holds research potential in studies of ER-mediated signaling endocrine-related diseases receptor-ligand binding analyses pharmacological screening and investigations of estrogen-dependent physiological and pathological conditions
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